According to Washington officials, there are only three Central American countries where U.S. citizens are not exposed to exceedingly high safety risks.
In other words, they are neither discouraged from visiting, nor are there specific travel warnings put in place.
If it’s Belize, Costa Rica, or Panama you’re headed, then you’re in luck: these are the safest travel destinations in Central America, as they are the only ones the U.S. State Department has added to their Level 2 Advisory, while all others fall under Level 3 or 4 categories.